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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1590810Generated: October 30, 2026

Water → L-Proline, 1-(1-oxohexyl)-

https://huagongshe.com/reaction/1590810

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantHCID 54249075HCID 54249075—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductL-Proline, 1-(1-oxohexyl)-HCID 1075108897.8%

Reaction Steps

10% Pd-C (3.00 g) was added to a 1% water-containing methanol solution (200 ml) of N-hexanoyl-L-proline benzyl ester (25.61 g), and the mixture was stirred under a hydrogen atmosphere at room temperature for 1.5 hours. After the catalyst was filtered off, the filtrate was concentrated to obtain 17.61 g of N-hexanoyl-L-proline.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05204462
Source datasetuspto-grants-1993_04
ORD IDord-9021ed3d5eaf4d45a77ef42ddc440104
Source noteuspto-grants-1993_04