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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1590811Generated: October 31, 2026

Water → 1-(5-Phenylpentanoyl)-L-proline

https://huagongshe.com/reaction/1590811

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantHCID 53780297HCID 53780297—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
Product1-(5-Phenylpentanoyl)-L-prolineHCID 5429493496.1%

Reaction Steps

10% Pd-C (1.40 g) was added to a 1% water-containing methanol solution (150 ml) of N-(5-phenylpentanoyl)-L-proline benzyl ester (13.87 g), and the mixture was stirred under a hydrogen atmosphere at room temperature for two hours. After the catalyst was filtered off, the filtrate was concentrated to obtain N-(5-phenylpentanoyl)-L-proline (10.04 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05204462
Source datasetuspto-grants-1993_04
ORD IDord-229f316f38984dd2b7084fadf2cbd338
Source noteuspto-grants-1993_04