HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 1-(5-Phenylpentanoyl)-L-proline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | HCID 53780297 | HCID 53780297 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 1-(5-Phenylpentanoyl)-L-proline | HCID 54294934 | 96.1% |
Reaction Steps
10% Pd-C (1.40 g) was added to a 1% water-containing methanol solution (150 ml) of N-(5-phenylpentanoyl)-L-proline benzyl ester (13.87 g), and the mixture was stirred under a hydrogen atmosphere at room temperature for two hours. After the catalyst was filtered off, the filtrate was concentrated to obtain N-(5-phenylpentanoyl)-L-proline (10.04 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05204462 |
| Source dataset | uspto-grants-1993_04 |
| ORD ID | ord-229f316f38984dd2b7084fadf2cbd338 |
| Source note | uspto-grants-1993_04 |