反应详情

A mixture of 15.0 g (59.1 mmol) of 1-cyclohexyloxy-2,2,6,6-tetramethylpiperidin-4-one, 3.4 g (29.6 mmol) of 1,6-hexanediamine, 500 mg of platinum oxide, and 150 ml of ethanol is hydrogenated in a Paar apparatus for 4 hours. The catalyst is removed by filtration. The filtrate is concentrated to an oil which is purified by flash chromatography (silica gel:ethyl acetate, then ethyl acetate:methanol) to afford 9.7 g {55% yield) of the title compound, as a yellow oil.

1. customThe catalyst is removed by filtration
2. concentrationThe filtrate is concentrated to an oil which
3. customis purified by flash chromatography (silica gel