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HRID 1591097作成日:2026年10月25日

4-Methyl-3-nitrobenzotrifluoride → 2-Methyl-5-(trifluoromethyl)aniline

https://huagongshe.com/reaction/1591097

反応式

関与物質

役割名称HCID仕込み量
反応物4-Methyl-3-nitrobenzotrifluorideHCID 1472885—
触媒PalladiumHCID 23938—
溶媒EthanolHCID 702—
生成物2-Methyl-5-(trifluoromethyl)anilineHCID 273593379.9%

反応手順

2-Methyl-5-trifluoromethylnitrobenzene (14.8 g) was dissolved in ethanol (100 ml) and hydrogenated at ambient temperature and pressure in the presence of palladium on charcoal (10%; 0.5 g). The solution was filtered and evaporated to dryness to give 2-methyl-5-trifluoromethylaniline (10.1 g) as a pale yellow oil.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US05206257
出典データセットuspto-grants-1993_04
ORD IDord-b60f6c0e4e074d2484a1a5236d4de3b2
出典メモuspto-grants-1993_04