化工社化工社 化学情報印刷レポート · 研究参考用
4-Methyl-3-nitrobenzotrifluoride → 2-Methyl-5-(trifluoromethyl)aniline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Methyl-3-nitrobenzotrifluoride | HCID 1472885 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 2-Methyl-5-(trifluoromethyl)aniline | HCID 2735933 | 79.9% |
反応手順
2-Methyl-5-trifluoromethylnitrobenzene (14.8 g) was dissolved in ethanol (100 ml) and hydrogenated at ambient temperature and pressure in the presence of palladium on charcoal (10%; 0.5 g). The solution was filtered and evaporated to dryness to give 2-methyl-5-trifluoromethylaniline (10.1 g) as a pale yellow oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05206257 |
| 出典データセット | uspto-grants-1993_04 |
| ORD ID | ord-b60f6c0e4e074d2484a1a5236d4de3b2 |
| 出典メモ | uspto-grants-1993_04 |