Potassium Carbonate → HCID 86746755, compound

Participants

Reaction Conditions

Reaction Steps

7.5 g (0.042 mol) of 3-(1-ethoxyiminoethyl)phenol and 10.0 g (0.035 mol) methyl α-(2-bromomethylphenyl)-β-methoxyacrylate are dissolved in 100 ml of dimethylformamide, and 7.3 g (0.053 mol) of potassium carbonate are added. The mixture is stirred at room temperature (20° C.) for 48 hours, hydrolyzed with water and extracted with diethyl ether. The organic phase is washed with water, dried over magnesium sulfate and concentrated. The resulting oil is purified by chromatography on alumina (cyclohexane). 7.3 g (54%) of the title compound are obtained as a colorless oil (compound no. 447).

Provenance & Evidence