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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1591340Generated: October 31, 2026

HCID 18956504, compound → HCID 18956546, compound

https://huagongshe.com/reaction/1591340

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 18956504HCID 18956504—
CatalystPotassium HydroxideHCID 14797—
SolventIsopropanolHCID 3776—
ProductHCID 18956546HCID 1895654684.6%

Reaction Steps

A solution of the product of Example 21 (70 mg) in isopropanol (4 ml) containing 50% aqueous potassium hydroxide (4 drops) was heated under reflux for 4 hours and then evaporated. Water was added to the residue and the mixture was extracted several times with ethyl acetate. The combined organic extracts were washed with water and dried (MgSO4). Evaporation of the solvent gave the title compound as an amorphous foam, (49 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05206364
Source datasetuspto-grants-1993_04
ORD IDord-957ef716b58c440eb07e4f49fac42fcd
Source noteuspto-grants-1993_04