Succinic Acid → Bis(2-(dimethylamino)ethyl) succinate

HRID 1591380Notes

Reaction equation

[C:1]([OH:8])(=[O:7])[CH2:2][CH2:3][C:4]([OH:6])=[O:5].[CH3:9][N:10]([CH2:12][CH2:13]O)[CH3:11]>>[C:1]([O:8][CH2:13][CH2:12][N:10]([CH3:11])[CH3:9])(=[O:7])[CH2:2][CH2:3][C:4]([O:6][CH2:13][CH2:12][N:10]([CH3:11])[CH3:9])=[O:5]

Participants

Reactant 2

HCID 1110Succinic Acid

HCID 79022-(Dimethylamino)ethanol

Product 1

HCID 87986Bis(2-(dimethylamino)ethyl) succinate

Procedure

In method I succinic acid is reacted with dimethylaminoethanol to give bis(2-dimethylaminoethyl) succinate, which is then reacted with methyl chloride to give succinylcholine chloride.

Sources & evidence

ORD record: ord-ef1e1c6debef4f278f38a57affd9f7eb
Source dataset: uspto-grants-1993_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05206420

Reaction notes

Loading…