3-((tert-Butoxycarbonyl)amino)-3-methylbutanoic acid → HCID 19025659, compound

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Reaction Steps

Prepared from 3-t-butoxycarbonylamino-3-methylbutanoic acid (Example 31, Step E) and the amine obtained in Step D by the procedure described in Example 1, Step F. 1H NMR (200 MHz, CDCl3): 1.44 (s,6H), 1.50 (s,9H), 1.80 (m,1H), 2.80 (m,5H), 3.86 (s,3H), 4.62 (m,1H), 6.62 (d,2 Hz,1H), 6.76 (dd;2,8 Hz;1H), 7.20 (d,8 Hz,1H). FAB-MS: calculated for C21H31N3O5 405; found 406 (M+H, 42%).

Provenance & Evidence