3-((tert-Butoxycarbonyl)amino)-3-methylbutanoic acid → HCID 19025696, compound

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Reaction Steps

Prepared from 3-t-butoxycarbonylamino-3-methylbutanoic acid (Example 31, Step E) and the amine obtained in Step H by the procedure described in Example 1, Step F. 1H NMR (200 MHz, CDCl3): 1.34 (s,6H), 1.42 (s,9H), 1.98 (m,1H), 2.50 (d,14 Hz,1H), 2.63 (d,14 Hz,1H), 2.7-3.0 (m,3H), 4.50 (m,1H), 6.75 (d,7 Hz,1H), 7.10 (d,8 Hz,1H), 7.51 (br s,2H), 7.94 (br s,1H). FAB-MS: calculated for C21H28F3N3O4 443; found 444 (M+H,74%).

Provenance & Evidence