3-((tert-Butoxycarbonyl)amino)-3-methylbutanoic acid → HCID 19025479, compound

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Reaction Steps

Prepared from 3-t-butoxycarbonylamino-3-methylbutanoic acid (Example 31, Step E) and the amine obtained in Step E by the procedure described in Example 1, Step F. 1H NMR (300 MHz, CDCl3): 1.35 (s,6H), 1.41 (s,9H), 1.93 (m,1H), 2.4-2.9 (m,5H), 4.54 (m,1H), 5.19 (br s,1H), 6.73 (m,2H), 6.88 (dt;2,8 Hz;1H), 7.19 (dd;6,8 Hz;1H), 8.07 (m,1H). FAB-MS: calculated for C20H28FN3O4 393; found 394 (M+H,56%).

Provenance & Evidence