4-Phenylbenzyl chloride → 3-t-Butoxycarbonylamino-3-methyl-N-[2,3,4,5-tetrahydro-2-oxo-1-[[[1,1'-biphenyl]-4-yl]methyl]-1H-1-benzazepin-3(R)-yl]-butanamide

Participants

Role	Name	HCID	Charge
Reactant	4-Phenylbenzyl chloride	HCID 15463	—
Reactant	3-t-butoxycarbonylamino-3-methyl-N-[2,3,4,5-tetrahydro-2-oxo-1H-benzazepin-3(R)-yl]butanamide	HCID 10474604	—
Product	3-t-Butoxycarbonylamino-3-methyl-N-[2,3,4,5-tetrahydro-2-oxo-1-[[[1,1'-biphenyl]-4-yl]methyl]-1H-1-benzazepin-3(R)-yl]-butanamide	HCID 18651478	—

Reaction Steps

Prepared from the intermediate obtained in Step A and 4-chloromethylbiphenyl by the procedure described in Example 1, Step K. FAB-MS: calculated for C33H39N3O4 541; found 542 (M+H,31%).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US05206235
Source dataset	uspto-grants-1993_04
ORD ID	ord-2c99cb87375a4d628537e42619fd97b5
Source note	uspto-grants-1993_04