Benzylamine → HCID 67751885, compound

Participants

Reaction Steps

The title compound was prepared from 4'-[[2,3,4,5-tetrahydro-3(R)-[[3-methyl-1-oxo-3-[(benzyloxycarbonyl)amino]butyl]amino]-2-oxo-1H-1-benzazepin-1-yl]methyl][1,1'-biphenyl]-2-carboxylic acid (Example 72, Step B) and benzylamine according to the procedure described in Example 74, Step A. 1H NMR (200 MHz,CDCl3): 1.31 (s,3H), 1.35 (s,3H), 1.75 (m,1H), 2.30-2.65 (m,5H), 4.23 (d,5 Hz,2H), 4.47 (m,1H), 4.83 (d,14 Hz,1H), 5.02 (s,2H), 5.45 (m,1H), 5.60 (s,1H), 6.68 (d,6 Hz,1H), 6.90 (m,2H), 7.10-7.50 (m,20H), 7.65 (m,1H). FAB-MS: calculated for C44H44N4O5 708; found 709 (M+H), 731 (M+Na,100%).

Provenance & Evidence