Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1591612Generated: October 25, 2026

4-Aminobenzyl alcohol → {4-[4-Chloro-6-(5-chloro-2-methyl-phenyl)-[1,3,5]triazin-2-ylamino]-phenyl}-methanol

https://huagongshe.com/reaction/1591612

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Aminobenzyl alcoholHCID 69331—
Reactant2,4-Dichloro-6-(5-chloro-2-methyl-phenyl)-[1,3,5]triazineHCID 85827032—
Product{4-[4-Chloro-6-(5-chloro-2-methyl-phenyl)-[1,3,5]triazin-2-ylamino]-phenyl}-methanolHCID 8658897062%

Reaction Steps

The reaction of 2,4-dichloro-6-(5-chloro-2-methyl-phenyl)-[1,3,5]triazine and 4-aminobenzyl alcohol using the method described in Example 37 provided the title compound (50 mg, 62% yield). 1H NMR (DMSO-d6) 9.52 (br s, 1H), 7.77 (s, 1H), 7.70 (s, 2H), 7.42 (d, 1H), 7.33 (d, 1H), 7.24 (m, 4H), 5.07 (m, 1H), 4.45 (d, J=5.7 Hz, 2H), 2.52 (s, 3H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07291616B2
Source datasetuspto-grants-2007_11
ORD IDord-6b18fb76683545d79c1c3470613d5094
Source noteuspto-grants-2007_11