4-(Pyrrolidin-3-yl)pyridine → 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[3-(4-pyridinyl)-1-pyrrolidinyl]-8-(trifluoromethyl)-3-quinolinecarboxylic acid

HRID 159178Notes

Reaction equation

HRID 159178 reaction equation
[CH:1]1([n:4]2[cH:5][c:6]([C:21](=[O:22])[OH:23])[c:7](=[O:20])[c:8]3[cH:9][c:10]([F:19])[c:11]([F:18])[c:12]([C:14]([F:15])([F:16])[F:17])[c:13]23)[CH2:2][CH2:3]1.[NH:24]1[CH2:25][CH:26]([c:29]2[cH:30][cH:31][n:32][cH:33][cH:34]2)[CH2:27][CH2:28]1>>[CH:1]1([n:4]2[cH:5][c:6]([C:21](=[O:22])[OH:23])[c:7](=[O:20])[c:8]3[cH:9][c:10]([F:19])[c:11]([N:24]4[CH2:25][CH:26]([c:29]5[cH:30][cH:31][n:32][cH:33][cH:34]5)[CH2:27][CH2:28]4)[c:12]([C:14]([F:15])([F:16])[F:17])[c:13]23)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 49931054-(Pyrrolidin-3-yl)pyridineHCID 142788301-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxo-8-trifluoromethyl-3-quinolinecarboxylic acid

Product 1

HCID 152312941-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[3-(4-pyridinyl)-1-pyrrolidinyl]-8-(trifluoromethyl)-3-quinolinecarboxylic acid

Sources & evidence

ORD record
ord-fe864eb365ad4baea643adcc757420a0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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