1-Butanesulfonyl chloride → HCID 16050903, compound

HRID 1591812Notes

Reaction equation

HRID 1591812 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:12]([CH3:13])[C:11]([C:14]#[N:15])=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.[CH2:16]([S:20](Cl)(=[O:22])=[O:21])[CH2:17][CH2:18][CH3:19]>>[C:14]([C:11]1[N:12]([CH3:13])[C:8]([C:5]2[CH:6]=[CH:7][C:2]([NH:1][S:20]([CH2:16][CH2:17][CH2:18][CH3:19])(=[O:22])=[O:21])=[CH:3][CH:4]=2)=[CH:9][CH:10]=1)#[N:15]

Participants

3

Reactant 2

HCID 754301-Butanesulfonyl chlorideHCID 160504305-(4-aminophenyl)-1-methyl-1H-pyrrole-2-carbonitrile

Product 1

HCID 16050903HCID 16050903, compound

Procedure

The title compound was prepared according to general procedure for sulfonylation of 5-(4-aminophenyl)-1-methyl-1H-pyrrole-2-carbonitrile using butane sulfonyl chloride (72 μL, 0.55 mmol) to provide N-[4-(5-cyano-1-methyl-1H-pyrrol-2-yl)phenyl]butane-1-sulfonamide (0.026 g).

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-5cf66db758d24ad980743c6a4b3d2e4b
Source dataset
uspto-grants-2007_11
Patent number
US07291643B2

Reaction notes

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