HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,2,2-Trifluoroethanesulfonyl chloride → N-[4-(5-cyano-1-methyl-1H-pyrrol-2-yl)phenyl]-2,2,2-trifluoroethanesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,2,2-Trifluoroethanesulfonyl chloride | HCID 74242 | — |
| Reactant | 5-(4-aminophenyl)-1-methyl-1H-pyrrole-2-carbonitrile | HCID 16050430 | — |
| Product | N-[4-(5-cyano-1-methyl-1H-pyrrol-2-yl)phenyl]-2,2,2-trifluoroethanesulfonamide | HCID 16050904 | — |
Reaction Steps
The title compound was prepared according to general procedure for sulfonylation of 5-(4-aminophenyl)-1-methyl-1H-pyrrole-2-carbonitrile using 2,2,2-trifluoro-ethanesulfonyl chloride (55 μL, 0.55 mmol) to provide N-[4-(5-cyano-1-methyl-1H-pyrrol-2-yl)phenyl]-2,2,2-trifluoroethanesulfonamide (0.014 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07291643B2 |
| Source dataset | uspto-grants-2007_11 |
| ORD ID | ord-450860515ed64987bf368fd75eb7127b |
| Source note | uspto-grants-2007_11 |