Benzenesulfonyl chloride → N-(4-(5-Cyano-1-methyl-1H-pyrrol-2-yl)phenyl)benzenesulfonamide

HRID 1591815Notes

Reaction equation

HRID 1591815 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:12]([CH3:13])[C:11]([C:14]#[N:15])=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.[C:16]1([S:22](Cl)(=[O:24])=[O:23])[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[C:14]([C:11]1[N:12]([CH3:13])[C:8]([C:5]2[CH:6]=[CH:7][C:2]([NH:1][S:22]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)(=[O:24])=[O:23])=[CH:3][CH:4]=2)=[CH:9][CH:10]=1)#[N:15]

Participants

3

Reactant 2

HCID 7369Benzenesulfonyl chlorideHCID 160504305-(4-aminophenyl)-1-methyl-1H-pyrrole-2-carbonitrile

Product 1

HCID 16050906N-(4-(5-Cyano-1-methyl-1H-pyrrol-2-yl)phenyl)benzenesulfonamide

Procedure

The title compound was prepared according to general procedure for sulfonylation of 5-(4-aminophenyl)-1-methyl-1H-pyrrole-2-carbonitrile using benzenesulfonyl chloride (70 μL, 0.55 mmol) to provide N-[4-(5-cyano-1-methyl-1H-pyrrol-2-yl)phenyl]benzene sulfonamide (0.046 g).

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-7a40c380453742368f5223b9472edfc8
Source dataset
uspto-grants-2007_11
Patent number
US07291643B2

Reaction notes

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