HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propargyl bromide → HCID 16051276, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propargyl bromide | HCID 7842 | — |
| Reactant | N-[4-(5-Cyano-1H-pyrrol-2-yl)phenyl]ethanesulfonamide | HCID 16051191 | — |
| Reactant | Potassium tert-butoxide | HCID 23665647 | — |
| Product | HCID 16051276 | HCID 16051276 | 6.3% |
Reaction Steps
N-[4-(5-cyano-1H-pyrrol-2-yl)phenyl]ethanesulfonamide (0.150 g, 0.54 mmol) was alkylated according to the procedure of Example 40 using potassium tert-butoxide (1.08 mL of a 1M solution, 1.08 mmol) and propargyl bromide (80% in toluene, 0.055 mL, 0.50 mmol) to afford the title compound (0.10 g, 6.3%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07291643B2 |
| Source dataset | uspto-grants-2007_11 |
| ORD ID | ord-29b23af0d1a541c6b46c4eb3d9c43bcd |
| Source note | uspto-grants-2007_11 |