HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene, (3-iodopropyl)- → N-{4-[5-cyano-1-(3-phenylpropyl)-1H-pyrrol-2-yl]phenyl}ethanesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene, (3-iodopropyl)- | HCID 138121 | — |
| Reactant | N-[4-(5-Cyano-1H-pyrrol-2-yl)phenyl]ethanesulfonamide | HCID 16051191 | — |
| Reactant | Potassium tert-butoxide | HCID 23665647 | — |
| Product | N-{4-[5-cyano-1-(3-phenylpropyl)-1H-pyrrol-2-yl]phenyl}ethanesulfonamide | HCID 16051277 | 10% |
Reaction Steps
N-[4-(5-cyano-1H-pyrrol-2-yl)phenyl]ethanesulfonamide (0.150 g, 0.54 mmol) was alkylated according to the procedure of Example 40 using potassium tert-butoxide (1.08 mL of a 1 M solution, 1.08 mmol) and 1-Iodo-3-phenylpropane (0.093 mL, 0.60 mmol) to afford the title compound (0.020 g, 10%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07291643B2 |
| Source dataset | uspto-grants-2007_11 |
| ORD ID | ord-bfbb3eb981954de1b449b95335c86d27 |
| Source note | uspto-grants-2007_11 |