Methanesulfonyl chloride → HCID 16051281, compound

HRID 1591848Notes

Reaction equation

HRID 1591848 reaction equation
[CH3:1][S:2](Cl)(=[O:4])=[O:3].[NH2:6][C:7]1[CH:12]=[CH:11][C:10]([C:13]2[N:17]([CH3:18])[C:16]([C:19]#[N:20])=[CH:15][CH:14]=2)=[CH:9][C:8]=1[C:21]#[N:22]>>[C:21]([C:8]1[CH:9]=[C:10]([C:13]2[N:17]([CH3:18])[C:16]([C:19]#[N:20])=[CH:15][CH:14]=2)[CH:11]=[CH:12][C:7]=1[NH:6][S:2]([CH3:1])(=[O:4])=[O:3])#[N:22]

Participants

3

Reactant 2

HCID 31297Methanesulfonyl chlorideHCID 691146525-(4-Amino-3-cyanophenyl)-1-methyl-1H-pyrrole-2-carbonitrile

Product 1

HCID 16051281HCID 16051281, compoundYield 74%

Procedure

This compound was prepared according to the procedure of Example 48 using methane-sulfonyl chloride (0.044 mL, 0.6 mmol) and 5-(4-amino-3-cyanophenyl)-1-methyl-1H-pyrrole-2-carbonitrile (0.100 g, 0.45 mmol) to afford the title compound (0.100 g, 50%).

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-0cc900bb89fe40b392c64a55380fe524
Source dataset
uspto-grants-2007_11
Patent number
US07291643B2

Reaction notes

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