4-Fluorobenzoyl chloride → HCID 66939216, compound

Participants

Reaction Steps

Prepare according to Example 69 starting with N-Methyl-N-(1-methyl-piperidin-4-yl)-pyridine-2,6-diamine (Preparation 34) (200 mg, 0.91 mmol) and 4-fluorobenzoyl chloride (160 μL, 1.36 mmol) to yield 309 mg (90%) of the title compound: mass spectrum (ion spray): m/z=343.3 (M+1); Analysis calc'd for C19H24N4OFCl.0.6H2O: C, 58.56; H, 6.52; N, 14.38. Found: C, 58.31; H, 6.37; N, 14.39; mp 250–2° C.

Provenance & Evidence