2-Chlorobenzoyl chloride → HCID 66939189, compound

Participants

Reaction Steps

Prepare according to procedure in Example 66 starting with N-methyl-N-(1-methyl-piperidin-4-yl)-pyridine-2,6-diamine (Preparation 34) (200 mg, 0.907 mmol), 2-chlorobenzoyl chloride (126 μL, 0.998 mmol), and 1,4-dioxane (10 mL) to yield 340 mg (95%) of the title compound: mass spectrum (ion spray): m/z=359.3 (M+1); Analysis calc'd for C19H24N4OCl2.0.5H2O: C, 56.44; H, 6.23; N, 13.86. Found: C, 56.21; H, 5.91; N, 14.23. mp 90–2° C.

Provenance & Evidence