反应详情

50 ml of saturated etheric hydrochloric add are added to a solution of 9.95 g of 2-(3,5-bis-trifluoromethyl-benzenesulfonylamino)-6,7-dihydro-4H-thiazolo[5,4-c]pyridine-5-carboxylic acid tert-butyl ester in 150 ml of CH2Cl2 and and the mixture obtained is stirred at RT for 4 hours. From the mixture obtained solvent is evaporated and the evaporation residue obtained is treated with diethylether. A solid precipitates, is filtrated off and dried. 2-(3,5-Bis-trifluoromethyl-benzenesulfonylamino)-4,5,6,7-tetrahydro-thiazolo[5,4-c]pyridin-5-ium hydrochloride salt is obtained.

1. addition50 ml of saturated etheric hydrochloric add
2. customthe mixture obtained
3. customFrom the mixture obtained solvent
4. customis evaporated
5. customthe evaporation residue obtained
6. customA solid precipitates
7. filtrationis filtrated off
8. customdried