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HRID1591944

反应详情

EQUATION

反应方程式

HRID 1591944 的结构方程式

REACTANTS

反应物

1
结构：CN1[C@H]2CC[C@@H]1[C@@H](c1ncc(-c3ccccc3)s1)[C@@H](c1ccc(Cl)cc1)C2.c1cscn1
HCID86587253

未命名化合物

PRODUCTS

生成物

1
结构：CN1[C@H]2CC[C@@H]1[C@@H](c1ncc(-c3ccccc3)s1)[C@@H](c1ccc(Cl)cc1)C2.Cl
HCID69274040

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CO
溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

The thiazole was converted into hydrochloride salt: 1H NMR (MeOD) 1.99 (m, 1H), 2.51 (m, 5H), 2.93 (s, 3H), 3.79 (m, 2H), 4.15 (m, 1H), 4.28 (m, 1H), 7.02 (d, J=8.5 Hz, 2H) 7.21 (d, J=8.5 Hz, 2H), 7.39 (m, 5H), 8.06 (s, 1H); mp 228-230° C.; Anal clacd. for C23H24CIN2S.H2O; C, 61.47; H, 5.83; N, 6.23; S, 7.13; Cl, 15.78. Found: C, 61.61; H, 5.76; N, 6.20; S, 7.51; Cl, 15.84; [α]D+27.430 (c, 0.11; CH3OH).