HCID 86591042, compound → HCID 67139584, compound

Participants

Reaction Steps

A mixture of the title C compound, 2-(2,4-dimethoxybenzyl)-5-(2,4-dinitrophenyl)-1,1-dioxo-1,2,5-thiadiazolidin-3-one (200 mg, 4.42 mmol) in 20 mL of MeOH/EtOAc (3:1) and 10% palladium on carbon (100 mg) is shaken under hydrogen atmosphere at 40 psi for 1 h. The catalyst is removed by filtration and the solvents are evaporated to afford 2-(2,4-dimethoxy-benzyl)-5-(2,4-diaminophenyl)-1,1-dioxo-1,2,5-thiadiazolidin-3-one as a brown solid: [M+1]+=393.

Provenance & Evidence