HCID 11372145, compound → HCID 11427849, compound

Participants

Reaction Conditions

Reaction Steps

The above formamide (249 mg, 0.672 mmol) was dissolved in 1 mL of concentrated HCl and 1 mL of water. The reaction mixture was heated in a SmithSynthesizer™ (Personal Chemistry) at 60° C. for 1 h. The solvent was removed in vacuo. The residue was recrystallized from MeOH to give a yellow solid. The solid was stirred in 5 mL of 2 M sodium carbonate solution for 6 h. The resulting yellow solid was collected by filtration, washed with water and air dried to provide the title compound (98 mg, 43%).

Provenance & Evidence