2-Naphthalenecarboxaldehyde → HCID 69426752, compound

Participants

Reaction Steps

To a suspension of tert-butyl triphenylphosphoranediylacetate (8.82 g, 23.4 mmol) in toluene (15 mL) was added a solution of 2-naphthaldehyde (2.82 g, 18.0 mmol) in toluene (15 mL). The mixture was stirred at room temperature for 18 hr and filtered. The filtrate was concentrated, subjected to silica gel column chromatography (ethyl acetate/hexane=1/30) and recrystallized (acetonitrile/water=1/2) to give the title compound as a colorless paste (4.1 g, yield 91%), melting point: 74-75° C.

Provenance & Evidence