phenyl 3-(1-methyl-1H-tetraazol-5-yl)phenylcarbamate → HCID 58997671, compound

Participants

Reaction Steps

The product of Step i (0.26 g, 0.69 mmol, 1 eq.), and phenyl 3-(1-methyl-1H-tetraazol-5-yl)phenylcarbamate (Example 1a, see below)(0.20 g, 0.69 mmol, 1 eq.) were dissolved in DMF (2 mL) at room temperature and stirred under N2 overnight. The DMF was stripped on the rotary evaporator and EtOAc was added (50 mL). This mixture was washed with water (3×50 mL), dried (MgSO4), stripped, and flash chromatographed in 3:1 Hexanes/EtOAc to 1:1 Hexanes/EtOAc to 100% EtOAc to yield 98 mg of a white glass. MS (AP+) detects (M+H)+=566.6.

Provenance & Evidence