phenyl 3-(1-methyl-1H-tetraazol-5-yl)phenylcarbamate → HCID 44447136, compound

Participants

Reaction Steps

The product of Step g (50 mg, 0.19 mmol, 1 eq.), phenyl 3-(1-methyl-1H-tetraazol-5-yl)phenylcarbamate (55 mg, 0.19 mmol, 1 eq.) and acetonitrile (3 mL) were mixed at 25° C. under N2 overnight. Worked up by stripping off the solvents then purifying the residue over silica gel in 100% EtOAc to 4:1 EtOAc/MeOH. Obtained 70 mg of a white glass as product. NMR (300 MHz, CDCl3) δ 7.86 (s, 1H); 7.6 (d, 1H, J=7 Hz); 7.38 (t, 1H, J=7 Hz); 7.29 (d, 1H, J=7 Hz); 7.20-7.00 (m, 2H); 6.92 (t, 2H, J=7 Hz); 4.13 (s, 3H) 4.05-3.85 (m, 1H); 3.80-3.60(m, 1H); 2.80-2.40 (m, 8H); 1.85-1.60 (m, 2H); 1.18 (d, 3H, J=7 Hz); 1.00 (t, 3H, J=7 Hz).

Provenance & Evidence