Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1592375Generated: October 25, 2026

N-(4-Aminobutyl)-N-methyl carbamic acid tert-butyl ester → {4-[(3,5-Dimethyl-pyridin-2-ylmethyl)-amino]-butyl}-methyl-carbamic acid tert-butyl ester

https://huagongshe.com/reaction/1592375

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(4-Aminobutyl)-N-methyl carbamic acid tert-butyl esterHCID 2756377—
Reactant3,5-Dimethylpyridine-2-carbaldehydeHCID 18731683—
Product{4-[(3,5-Dimethyl-pyridin-2-ylmethyl)-amino]-butyl}-methyl-carbamic acid tert-butyl esterHCID 58997083—

Reaction Steps

Yellow oil prepared from 3,5-dimethyl-pyridine-2-carbaldehyde and (4-amino-butyl)-methyl-carbamic acid tert-butyl ester. 1H NMR (CDCl3) δ 1.44 (s, 9H), 1.53-1.57 (m, 4H), 2.27 (s, 6H), 2.69-2.73 (m, 2H), 2.82 (s, 3H), 3.18-3.23 (m, 2H), 3.83 (s, 2H), 7.24 (s, 1H), 8.20 (s, 1H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07291631B2
Source datasetuspto-grants-2007_11
ORD IDord-6ae80f4c59544f75936b281d881a6fa9
Source noteuspto-grants-2007_11