HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium triacetoxyborohydride → (3,5-dimethyl-pyridin-2-ylmethyl)-{2-[1-(toluene-4-sulfonyl)-1H-imidazol-4-yl]-ethyl}-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Reactant | 3,5-Dimethylpyridine-2-carbaldehyde | HCID 18731683 | — |
| Reactant | 2-[1-(toluene-4-sulfonyl)-1H-imidazol-4-yl]-ethylamine | HCID 54003537 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | (3,5-dimethyl-pyridin-2-ylmethyl)-{2-[1-(toluene-4-sulfonyl)-1H-imidazol-4-yl]-ethyl}-amine | HCID 67273302 | — |
Reaction Steps
Using General Procedure B: Reaction of 2-[1-(toluene-4-sulfonyl)-1H-imidazol-4-yl]-ethylamine and 3,5-dimethyl-pyridine-2-carbaldehyde in CH2Cl2 with NaBH(OAc)3 gave (3,5-dimethyl-pyridin-2-ylmethyl)-{2-[1-(toluene-4-sulfonyl)-1H-imidazol-4-yl]-ethyl}-amine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07291631B2 |
| Source dataset | uspto-grants-2007_11 |
| ORD ID | ord-d74f36175e2d4e3a8b7dc96d8304b874 |
| Source note | uspto-grants-2007_11 |