HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-butyl N-(4-aminobutyl)carbamate → {4-[1-(3-Methylpyridin-2-yl)-ethylamino]-butyl}-carbamic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-butyl N-(4-aminobutyl)carbamate | HCID 4351 | — |
| Reactant | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Reactant | 1-(3-Methylpyridin-2-yl)ethan-1-one | HCID 13068669 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | {4-[1-(3-Methylpyridin-2-yl)-ethylamino]-butyl}-carbamic acid tert-butyl ester | HCID 67272873 | — |
Reaction Steps
Using General Procedure B, 1-(3-methylpyridin-2-yl)-ethanone (Sundberg, R J et al. J. Am. Chem. Soc. 1969, 91, 658-668), (4-aminobutyl)-carbamic acid tert-butyl ester and NaBH(OAc)3 were reacted in CH2Cl2 to obtain {4-[1-(3-methylpyridin-2-yl)-ethylamino]-butyl}-carbamic acid tert-butyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07291631B2 |
| Source dataset | uspto-grants-2007_11 |
| ORD ID | ord-aa63716ece674a1ab12f919c40c12881 |
| Source note | uspto-grants-2007_11 |