反应详情

A solution of the above nitrile (258 mg, 0.69 mmol) in MeOH saturated with NH3 (15 mL) was hydrogenated (40 psi) over Raney-nickel for 4 hours. The mixture was filtered with suction through a pad of celite, washing with excess MeOH. The filtrate was concentrated under reduced pressure, giving the crude amine as a purple foam.

1. customfor 4 hours
2. filtrationThe mixture was filtered with suction through a pad of celite
3. washwashing with excess MeOH
4. concentrationThe filtrate was concentrated under reduced pressure