1-Bromo-4-ethylbenzene → HCID 68438886, compound

HRID 1592823Notes

Reaction equation

HRID 1592823 reaction equation
Br[C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH3:9])=[CH:4][CH:3]=1.C([O:17][C:18]1[C:22]([CH:23]=O)=[C:21]([CH3:25])[N:20]([C:26]2[CH:31]=[CH:30][C:29]([F:32])=[CH:28][CH:27]=2)[N:19]=1)C1C=CC=CC=1.C(OC1C(C=O)=C(C)N(C2C=CC=CC=2)N=1)C1C=CC=CC=1>>[CH2:8]([C:5]1[CH:6]=[CH:7][C:2]([CH2:23][C:22]2[C:18](=[O:17])[NH:19][N:20]([C:26]3[CH:27]=[CH:28][C:29]([F:32])=[CH:30][CH:31]=3)[C:21]=2[CH3:25])=[CH:3][CH:4]=1)[CH3:9]

Participants

4

Reactant 3

HCID 153131-Bromo-4-ethylbenzeneHCID 17863259HCID 17863259, compoundHCID 86592806HCID 86592806, compound

Product 1

HCID 68438886HCID 68438886, compound

Procedure

The title compound was prepared in a similar manner to that described in Example 1 using 1-bromo-4-ethylbenzene and 3-benzyloxy-1-(4-fluorophenyl)-4-formyl-5-methyl-1H-pyrazole instead of 4-bromoanisole and 3-benzyloxy-4-formyl-5-methyl-1-phenyl-1H-pyrazole, respectively.

Sources & evidence

ORD record
ord-659e4e50155f42cd8efb2e49c1072f41
Source dataset
uspto-grants-2007_11
Patent number
US07294618B2

Reaction notes

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