HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → HCID 69433927, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 1-Chloroethyl chloroformate | HCID 521305 | — |
| Reactant | HCID 69433981 | HCID 69433981 | — |
| Product | HCID 69433927 | HCID 69433927 | 178.5% |
Reaction Steps
Debenzylation of (2R)-2-((R)-[2,5-dichlorophenyl][phenylthio]methyl)-4-benzylmorpholine (174 mg, 0.39 mmol) with polymer supported Hunig's base (0.20 g, 0.78 mmol) and α-chloroethyl chloroformate (111 mg, 0.78 mmol) following the procedure described in example 1(iv) gave after SCX chromatography the product as an oil (136 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07294623B2 |
| Source dataset | uspto-grants-2007_11 |
| ORD ID | ord-fcbcb3c5552d46b2b7e67314edf9e4ae |
| Source note | uspto-grants-2007_11 |