HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Benzyl-4-piperidone → HCID 21559974, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Benzyl-4-piperidone | HCID 19220 | — |
| Reactant | Benzene, 1-bromo-4-(trifluoromethyl)- | HCID 67872 | — |
| Reactant | Magnesium | HCID 5462224 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 21559974 | HCID 21559974 | 41.2% |
Reaction Steps
This compound is prepared by the procedure described in step A of preparation 1.7, from 1.55 g of magnesium in 25 ml of THF, a solution of 14.25 g of 1-bromo-4-(trifluoromethyl)benzene in 15 ml of THF and a solution of 10 g of 1-benzyl-4-piperidinone in 30 ml of THF. This gives 7.3 g of the expected product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07294628B2 |
| Source dataset | uspto-grants-2007_11 |
| ORD ID | ord-4f16f63d59f04e30b1d4754352107abf |
| Source note | uspto-grants-2007_11 |