2-(2-t-Butoxycarbonylaminopyridin-4-yl)-3-dimethylamino-1-(3-fluorophenyl)-2-propen-1-one → HCID 178452640, compound

Participants

Reaction Steps

The reaction was carried out in the same manner as in Example 2-2) except for using 13.5 g (35.0 mmol) of 2-(2-t-butoxycarbonylaminopyridin-4-yl)-3-dimethylamino-1-(3-fluorophenyl)-2-propen-1-one obtained in Example 22-1) in place of 2-(2-t-butoxycarbonylaminopyridin-4-yl)-3-dimethylamino-1-(4-fluorophenyl)-2-propen-1-one to obtain 12.4 g of the title compound as a yellowish white powder. (Yield: quantitative)

Provenance & Evidence