HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl acetoacetate → HCID 58999059, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl acetoacetate | HCID 7757 | — |
| Reactant | 1-Aminopiperidine | HCID 16658 | — |
| Reactant | Cyclopropanemethanamine | HCID 75646 | — |
| Reactant | 3,5-Bis(trifluoromethyl)phenacyl bromide | HCID 2736170 | — |
| Product | HCID 58999059 | HCID 58999059 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 68, using 3-oxo-butyric acid methyl ester as compound of formula R, 1-(3,5-Bis-trifluoromethyl-phenyl)-2-bromo-ethanone as compound of formula S, cyclopropanemethylamine as R3—(CH2)m—NH2 and 1-piperidinamine as R1R2NH, MS (ISP) 474.3 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07294644B2 |
| Source dataset | uspto-grants-2007_11 |
| ORD ID | ord-a461864594f14bb6813c456330110d36 |
| Source note | uspto-grants-2007_11 |