HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl acetoacetate → HCID 86594075, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl acetoacetate | HCID 7757 | — |
| Reactant | Cyclopropanemethanamine | HCID 75646 | — |
| Reactant | (1R,2R)-2-Aminocyclohexanol | HCID 735777 | — |
| Reactant | 2-Bromo-1-(5-fluoro-2-methoxyphenyl)ethanone | HCID 2756985 | — |
| Product | HCID 86594075 | HCID 86594075 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 68, using 3-oxo-butyric acid methyl ester as compound of formula R, 2-bromo-1-(5-fluoro-2-methoxy-phenyl)-ethanone as compound of formula S, cyclopropanemethylamine as R3—(CH2)m—NH2 and trans-2-hydroxy-cyclohexylamine as R1R2NH, MS (ISP) 401.6 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07294644B2 |
| Source dataset | uspto-grants-2007_11 |
| ORD ID | ord-2452ec6da34c4f05ab78297304645018 |
| Source note | uspto-grants-2007_11 |