huagongshe.com
HRID1593182

反应详情

EQUATION

反应方程式

HRID 1593182 的结构方程式

REACTANTS

反应物

4
结构：COC(=O)CC(C)=O
HCID7757

Methyl acetoacetate

C5H8O3

结构：NC1CCCCC1
HCID7965

Cyclohexylamine

C6H13N

结构：O=C(CBr)c1cc(C(F)(F)F)ccc1F
HCID2778784

2-Bromo-1-[2-fluoro-5-(trifluoromethyl)phenyl]ethan-1-one

C9H5BrF4O

结构：NC[C@H]1CC[C@H](O)CC1
HCID178511287

未命名化合物

PRODUCTS

生成物

1
结构：Cc1c(C(=O)NC2CCCCC2)cc(-c2cc(C(F)(F)F)ccc2F)n1CC1CCC(O)CC1
HCID58999142

未命名化合物

PROCEDURE

实验过程

The title compound was synthesized in analogy to Example 68, using 3-oxo-butyric acid methyl ester as compound of formula R, 2-bromo-1-(2-fluoro-5-trifluoromethyl-phenyl)-ethanone as compound of formula S, trans-4-(aminomethyl)-cyclohexanol, as R3—(CH2)m—NH2 and cyclohexylamine as R1R2NH, MS (ISP) 481.6 (M+H)+.