HRID1593238

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COc1ccc(NS(=O)(=O)c2ccc(OCC(=O)OCCS(=O)(=O)c3ccc(C)cc3)c(OCC(=O)OCCS(=O)(=O)c3ccc(C)cc3)c2)c([N+](=O)[O-])c1

HCID22479324

未命名化合物

PRODUCTS

生成物

结构：COc1ccc(NS(=O)(=O)c2ccc(OCC(=O)OCCS(=O)(=O)c3ccc(C)cc3)c(OCC(=O)OCCS(=O)(=O)c3ccc(C)cc3)c2)c(N)c1

HCID22479343

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

催化剂HCID82844

Platinum oxide (PtO)

OPt

PROCEDURE

实验过程

2(4-Tolylsulfonyl)ethyl 4-(4-methoxy-2-nitro-phenyl)aminosulfonyl-2-(2-[4-tolylsulfonyl]ethoxycarbonylmethoxy)phenoxyacetate (Intermediate A17, 6.6 g, 0.0080 mol) was hydrogenated using platinum oxide as catalyst. The mixture was filtered and concentrated. After drying at high vacuum, the residual product, title compound, weighed 5.9 g (93%).

WORKUP

后处理

filtrationThe mixture was filtered
concentrationconcentrated
customAfter drying at high vacuum

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-5e6087222d8841e3bd559dd428ad9532
来源数据集: uspto-grants-2007_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07294716B2
来源说明: uspto-grants-2007_11

反应 SMILES

[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([NH:9][S:10]([C:13]2[CH:35]=[CH:34][C:16]([O:17][CH2:18][C:19]([O:21][CH2:22][CH2:23][S:24]([C:27]3[CH:32]=[CH:31][C:30]([CH3:33])=[CH:29][CH:28]=3)(=[O:26])=[O:25])=[O:20])=[C:15]([O:36][CH2:37][C:38]([O:40][CH2:41][CH2:42][S:43]([C:46]3[CH:51]=[CH:50][C:49]([CH3:52])=[CH:48][CH:47]=3)(=[O:45])=[O:44])=[O:39])[CH:14]=2)(=[O:12])=[O:11])=[C:5]([N+:53]([O-])=O)[CH:4]=1>[Pt]=O>[NH2:53][C:5]1[CH:4]=[C:3]([O:2][CH3:1])[CH:8]=[CH:7][C:6]=1[NH:9][S:10]([C:13]1[CH:35]=[CH:34][C:16]([O:17][CH2:18][C:19]([O:21][CH2:22][CH2:23][S:24]([C:27]2[CH:28]=[CH:29][C:30]([CH3:33])=[CH:31][CH:32]=2)(=[O:25])=[O:26])=[O:20])=[C:15]([O:36][CH2:37][C:38]([O:40][CH2:41][CH2:42][S:43]([C:46]2[CH:51]=[CH:50][C:49]([CH3:52])=[CH:48][CH:47]=2)(=[O:44])=[O:45])=[O:39])[CH:14]=1)(=[O:11])=[O:12]