Hydrochloric Acid → HCID 66918130, compound

Participants

Reaction Conditions

Reaction Steps

To a stirred solution of {4-{4-[bis-(4-fluorophenyl)methyl]-piperazin-1-yl}-(Z)-but-2-enyloxy}acetic acid (1.0 g, 0.0024 mol) in ethanol (20 ml), is added a solution of anhydrous ethanolic HCl till pH is 1-2. The solution is refluxed for around 2 hrs, cooled to 25-30° C. and stirred for 4 hrs. The crystallized solid is filtered, washed with ethanol (2×5 ml), and dried in oven at 60-65° C. to get the product.

Provenance & Evidence