Ammonium Acetate → HCID 86595409, compound

Participants

Reaction Steps

A solution of the product of Step 4 (0.45 g, 1 mmol) and ammonium acetate (0.77 g, 10 mmol) in glacial acetic acid (15 ml) was heated under reflux for 3 hours. After cooling to room temperature the reaction mixture was concentrated in vacuo and saturated sodium hydrogen carbonate solution was added. The mixture was extracted with chloroform and the organic phase washed with water and brine, dried and concentrated in vacuo to afford the title compound (0.47 g, 100%); MS(ES+) m/e 467 [M+H]+.

Provenance & Evidence