Phosphorus oxide (P4O10) → HCID 86595412, compound

Participants

Reaction Steps

The product of Example 1 Step 4 (0.30 mg, 0.62 mmol) was added to a stirred suspension of phosphorus pentoxide (1 g) in dry methane sulphonic acid (5 ml). After stirring at room temperature for 2 hours the reaction mixture was cautiously poured into a stirred solution of saturated aqueous sodium hydrogen carbonate. The mixture was extracted with ethyl acetate and the organic phase washed with water and saturated brine, dried (MgSO4) and concentrated in vacuo to afford the title compound (0.28 g, 96%); MS(ES+) m/e 468 [M+H]+.

Provenance & Evidence