2,3-Dibromofuran → 5-(3-Bromofuran-2-yl)indan-1-one o-methyloxime

HRID 1593444Notes

Reaction equation

HRID 1593444 reaction equation
Br[C:2]1[O:3][CH:4]=[CH:5][C:6]=1[Br:7].[CH3:8][O:9][N:10]=[C:11]1[C:19]2[C:14](=[CH:15][C:16](B(O)O)=[CH:17][CH:18]=2)[CH2:13][CH2:12]1>>[CH3:8][O:9][N:10]=[C:11]1[C:19]2[C:14](=[CH:15][C:16]([C:2]3[O:3][CH:4]=[CH:5][C:6]=3[Br:7])=[CH:17][CH:18]=2)[CH2:13][CH2:12]1

Participants

3

Reactant 2

HCID 70215012,3-DibromofuranHCID 734146811-Methoxyimino-indan-5-boronic acid

Product 1

HCID 862135945-(3-Bromofuran-2-yl)indan-1-one o-methyloximeYield 30%

Procedure

The title compound (1.6 g, 30%) was prepared from 2,3-dibromofuran and the product of Example 5 Step 6 using the method of Example 15 Step 1; 1H NMR (CDCl3) 7.88 (2H, m), 7.72 (1H, d, J 8.3 Hz), 7.42 (2H, d, J 3.1 Hz), 4.01 (3H, s), 3.17 (2H, m), 2.92 (2H, m).

Sources & evidence

ORD record
ord-db0c413ad62247989eb544813f9555b0
Source dataset
uspto-grants-2007_11
Patent number
US07297694B2

Reaction notes

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