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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1593555Generated: October 30, 2026

Isobutyryl chloride → N-[4-(5-Cyano-1-methyl-1H-pyrrol-2-yl)phenyl]-2-methylpropanamide

https://huagongshe.com/reaction/1593555

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsobutyryl chlorideHCID 62325—
Reactant5-(4-aminophenyl)-1-methyl-1H-pyrrole-2-carbonitrileHCID 16050430—
ProductN-[4-(5-Cyano-1-methyl-1H-pyrrol-2-yl)phenyl]-2-methylpropanamideHCID 16037461—

Reaction Steps

The title compound was prepared according to the general procedure for acylation of 5-(4-aminophenyl)-1-methyl-1H-pyrrole-2-carbonitrile using isobutyryl chloride (58 μL, 0.55 mmol) to provide N-[4-(5-cyano-1-methyl-1H-pyrrol-2-yl)phenyl]-2-methylpropanamide (0.026 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07297713B2
Source datasetuspto-grants-2007_11
ORD IDord-4b00b7af2b2846b086588b74169dfb62
Source noteuspto-grants-2007_11