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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1593556Generated: October 31, 2026

Propionyl chloride → N-[4-(5-cyano-1-methyl-1H-pyrrol-2-yl)phenyl]propanamide

https://huagongshe.com/reaction/1593556

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPropionyl chlorideHCID 62324—
Reactant5-(4-aminophenyl)-1-methyl-1H-pyrrole-2-carbonitrileHCID 16050430—
ProductN-[4-(5-cyano-1-methyl-1H-pyrrol-2-yl)phenyl]propanamideHCID 16037462—

Reaction Steps

The title compound was prepared according to the general procedure for acylation of 5-(4-aminophenyl)-1-methyl-1H-pyrrole-2-carbonitrile using propionyl chloride (48 μL, 0.55 mmol) to provide N-[4-(5-cyano-1-methyl-1H-pyrrol-2-yl)phenyl]propanamide (0.012 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07297713B2
Source datasetuspto-grants-2007_11
ORD IDord-84afc0fcbdd145f88138f37f0d2892c3
Source noteuspto-grants-2007_11