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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1593560Generated: October 31, 2026

Cyclobutanecarbonyl chloride → N-[4-(5-cyano-1-methyl-1H-pyrrol-2-yl)phenyl]cyclobutane carboxamide

https://huagongshe.com/reaction/1593560

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclobutanecarbonyl chlorideHCID 78705—
Reactant5-(4-aminophenyl)-1-methyl-1H-pyrrole-2-carbonitrileHCID 16050430—
ProductN-[4-(5-cyano-1-methyl-1H-pyrrol-2-yl)phenyl]cyclobutane carboxamideHCID 16037547—

Reaction Steps

The title compound was prepared according to the general procedure for acylation of 5-(4-aminophenyl)-1-methyl-1H-pyrrole-2-carbonitrile using cyclobutane carbonyl chloride (60 μL, 0.55 mmol) to provide N-[4-(5-cyano-1-methyl-1H-pyrrol-2-yl)phenyl]cyclobutane carboxamide (0.048 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07297713B2
Source datasetuspto-grants-2007_11
ORD IDord-cdacd28bffe24f11972a4d73899e8c71
Source noteuspto-grants-2007_11