Cyanogen Bromide → [(4-Bromophenyl)methyl]cyanamide

Participants

Reaction Steps

A mixture of cyanogen bromide (3.18 g, 30 mmol), and (4-bromophenyl) methyl aniline (11.25 g, 61 mmol) in ether (50 mL) was stirred for 3 days under nitrogen. The mixture was filtered, the filtrate evaporated, and the residue flash chromatographed on silica gel using 9/1 Hexane/acetone to give (4-bromophenyl)methylcyanamide (2 g, 16 %).

Provenance & Evidence