Triphenylphosphine → HCID 58999575, compound

Participants

Reaction Steps

4-azido-7-benzyl-5,6,7,8-tetrahydro-1,7-naphthyridine (0.06 g, 0.226 mmol) was treated with 0.5 g of PS-PPh3 resin in a 8 ml mixture THF:H2O (18:1) at 32° C. ON. The reaction was monitored by LCMS and TLC. The reaction mixture was filtered and washed with THF and methanol. The combined filtrate was concentrated and used directly in the next step.

Provenance & Evidence